PBR Antibody

Flow Cytometry: PBR Antibody [NB100-41398]

Flow Cytometry: PBR Antibody [NB100-41398] - Flow cytometric analysis of paraformaldehyde fixed MCF7 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Immunocytochemistry/ Immunofluorescence: PBR Antibody [NB100-41398]

Immunocytochemistry/Immunofluorescence: PBR Antibody [NB100-41398] - Immunofluorescence analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative cLontrol: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody.

Immunohistochemistry-Paraffin: PBR Antibody [NB100-41398]

Immunohistochemistry-Paraffin: PBR Antibody [NB100-41398] - Staining of paraffin embedded Human Colon. Antibody at 2.5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Immunohistochemistry-Paraffin: PBR Antibody [NB100-41398]

Immunohistochemistry-Paraffin: PBR Antibody [NB100-41398] - Staining of paraffin embedded Human Kidney. Antibody at 5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Immunohistochemistry: PBR Antibody [NB100-41398]

PBR-Antibody-Immunohistochemistry-NB100-41398-img0012.jpg

Immunohistochemistry: PBR Antibody [NB100-41398] -

Immunohistochemistry: PBR Antibody [NB100-41398] - [18F]PBR06 selectivity in primary human grade IV glioblastoma xenotransplant.(A) Dynamic PET image (axial) pre-infusion of cold analog, with [18F]PBR06 uptake primarily confined to the tumor. (B) Dynamic PET image (axial) post-infusion, showing nearly total displacement of [18F]PBR06. (C) Time-activity curves of injected [18F]PBR06 in tumor (green) & contralateral brain (blue). (D) Correlative TSPO immunohistochemistry, Tumor + White Matter Tract (40X). Image collected & cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0141659), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Immunohistochemistry-Paraffin: PBR Antibody [NB100-41398] -

Immunohistochemistry-Paraffin: PBR Antibody [NB100-41398] - Human tumor microarrays (TMAs).Pilocytic astrocytoma TSPO immunohistochemistry (A) & TSPO immunohistochemical scoring (C). Glioblastoma multiforme TSPO immunohistochemistry (B) & TSPO immunohistochemical scoring (D). Image collected & cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0141659), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Immunohistochemistry-Paraffin: PBR Antibody [NB100-41398] -

Immunohistochemistry-Paraffin: PBR Antibody [NB100-41398] - Human tumor microarrays (TMAs).Pilocytic astrocytoma TSPO immunohistochemistry (A) & TSPO immunohistochemical scoring (C). Glioblastoma multiforme TSPO immunohistochemistry (B) & TSPO immunohistochemical scoring (D). Image collected & cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0141659), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Immunohistochemistry-Paraffin: PBR Antibody [NB100-41398] -

Immunohistochemistry-Paraffin: PBR Antibody [NB100-41398] - Primary human grade IV glioblastoma xenotransplant.(A) Dynamic PET image (coronal) of advanced tumor in the right hemisphere of the brain with [18F]PBR06 uptake confined primarily to the tumor. Arrows indicate tumor & infiltration into left hemisphere. (B) Time-activity curves of injected [18F]PBR06 in tumor (green) & contralateral brain (blue) [30]. (C) Correlative TSPO immunohistochemistry, Tumor + White Matter Tract (40X). Image collected & cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0141659), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Immunohistochemistry-Paraffin: PBR Antibody [NB100-41398] -

Immunohistochemistry-Paraffin: PBR Antibody [NB100-41398] - Primary human grade III astrocytoma xenotransplant.(A) T2-weighted MRI (coronal) visualizes advanced tumor in the right hemisphere of the brain. (B) Correlative dynamic PET image (coronal) of same advanced tumor in the right hemisphere of the brain, with [18F]PBR06 uptake primarily confined to the tumor & co-localizing with tumor tissue visualized by MRI. Top arrows indicate tumor & infiltration into left hemisphere. (C) Fused MRI (A) PET (B) image. (D) Time-activity curves of injected [18F]PBR06 in tumor (green) & contralateral brain (blue). Correlative vimentin immunohistochemistry: (E) Gross; (F) Tumor + White Matter Tract (40X); (G) Tumor (40X). (H) Correlative dynamic PET image, axial view along yellow line in (B); arrows indicate tumor & infiltration into left hemisphere. Correlative TSPO immunohistochemistry: (I) Gross; (J) Tumor + White Matter Tract (40X); (K) Tumor (40X). (L) Dynamic PET image (axial) of control cohort. Correlative CD68 immunohistochemistry: (M) Gross; (N) Tumor + White Matter Tract (40X); (O) Tumor (40X). Image collected & cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0141659), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Immunohistochemistry-Paraffin: PBR Antibody [NB100-41398] -

Immunohistochemistry-Paraffin: PBR Antibody [NB100-41398] - Primary human grade III astrocytoma xenotransplant.(A) T2-weighted MRI (coronal) visualizes advanced tumor in the right hemisphere of the brain. (B) Correlative dynamic PET image (coronal) of same advanced tumor in the right hemisphere of the brain, with [18F]PBR06 uptake primarily confined to the tumor & co-localizing with tumor tissue visualized by MRI. Top arrows indicate tumor & infiltration into left hemisphere. (C) Fused MRI (A) PET (B) image. (D) Time-activity curves of injected [18F]PBR06 in tumor (green) & contralateral brain (blue). Correlative vimentin immunohistochemistry: (E) Gross; (F) Tumor + White Matter Tract (40X); (G) Tumor (40X). (H) Correlative dynamic PET image, axial view along yellow line in (B); arrows indicate tumor & infiltration into left hemisphere. Correlative TSPO immunohistochemistry: (I) Gross; (J) Tumor + White Matter Tract (40X); (K) Tumor (40X). (L) Dynamic PET image (axial) of control cohort. Correlative CD68 immunohistochemistry: (M) Gross; (N) Tumor + White Matter Tract (40X); (O) Tumor (40X). Image collected & cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0141659), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Immunohistochemistry: PBR Antibody [NB100-41398] -

Immunohistochemistry: PBR Antibody [NB100-41398] - Primary human grade III astrocytoma xenotransplant.(A) T2-weighted MRI (coronal) visualizes advanced tumor in the right hemisphere of the brain. (B) Correlative dynamic PET image (coronal) of same advanced tumor in the right hemisphere of the brain, with [18F]PBR06 uptake primarily confined to the tumor & co-localizing with tumor tissue visualized by MRI. Top arrows indicate tumor & infiltration into left hemisphere. (C) Fused MRI (A) PET (B) image. (D) Time-activity curves of injected [18F]PBR06 in tumor (green) & contralateral brain (blue). Correlative vimentin immunohistochemistry: (E) Gross; (F) Tumor + White Matter Tract (40X); (G) Tumor (40X). (H) Correlative dynamic PET image, axial view along yellow line in (B); arrows indicate tumor & infiltration into left hemisphere. Correlative TSPO immunohistochemistry: (I) Gross; (J) Tumor + White Matter Tract (40X); (K) Tumor (40X). (L) Dynamic PET image (axial) of control cohort. Correlative CD68 immunohistochemistry: (M) Gross; (N) Tumor + White Matter Tract (40X); (O) Tumor (40X). Image collected & cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0141659), licensed under a CC-BY license. Not internally tested by Novus Biologicals.