PD-1 Antibody (CL3624) - BSA Free

Novus Biologicals | Catalog # NBP2-61625

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL3624

Format

BSA Free
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Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from Q15116, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for PD-1 Antibody (CL3624) - BSA Free

Western Blot: PD-1 Antibody (CL3624) [NBP2-61625]

Western Blot: PD-1 Antibody (CL3624) [NBP2-61625]

Western Blot: PD-1 Antibody (CL3624) [NBP2-61625] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10
Lane 2: Negative control (vector only transfected HEK293T lysate)
Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells)
Immunohistochemistry: PD-1 Antibody (CL3624) [NBP2-61625]

Immunohistochemistry: PD-1 Antibody (CL3624) [NBP2-61625]

Immunohistochemistry: PD-1 Antibody (CL3624) [NBP2-61625] - Staining of human liver shows absence of immunoreactivity (negative control).
Immunohistochemistry: PD-1 Antibody (CL3624) [NBP2-61625]

Immunohistochemistry: PD-1 Antibody (CL3624) [NBP2-61625]

Immunohistochemistry: PD-1 Antibody (CL3624) [NBP2-61625] - Staining of human tonsil shows strong immunoreactivity in a subset of lymphoid cells, mainly in the reaction centrum.

Applications for PD-1 Antibody (CL3624) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

1 ug/ml
Application Notes
IHC-Paraffin HIER pH6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PD-1

PD1 is an inhibitory cell membrane surface receptor from the immunoglobulin superfamily. Involved in the regulation of T cell function during immunity and tolerance, PD1 inhibits T cell effector functions upon ligand binding. The protein is expressed in pro-B-cells and is thought to play a role in their differentiation as well. Studies have also suggested that this gene product may also contribute to the prevention of autoimmune diseases.

Long Name

Programmed Death-1

Alternate Names

CD279, PD1, PDCD1, SLEB2

Gene Symbol

PDCD1

Additional PD-1 Products

Product Documents for PD-1 Antibody (CL3624) - BSA Free

Certificate of Analysis

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Product Specific Notices for PD-1 Antibody (CL3624) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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