PDGFR alpha Antibody (BLR078G)

Name: PDGFR alpha Antibody (BLR078G)
Brand: Novus Biologicals
SKU: NBP3-14686
Price: 519 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-14686

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit Clone # BLR078G

View all PDGF R alpha Primary Antibodies »

Product Specifications

Immunogen

residues 24-525 (ECD)

Clonality

Monoclonal

Host

Rabbit

Scientific Data Images for PDGFR alpha Antibody (BLR078G)

Immunoprecipitation: PDGFR alpha Antibody (BLR078G) [NBP3-14686]

Immunoprecipitation: PDGFR alpha Antibody [NBP3-14686] - Whole cell lysate (1.0 mgper IP reaction; 20% of IP loaded) from NCI-H1703 cellsprepared using NETN lysis buffer. Antibodies: Rabbit antiPDGFR alpha recombinant monoclonal antibody used for IP at 20 ul/mg lysate. PDGFRalpha was also immunoprecipitated by rabbit anti-PDGFR alpha recombinant monoclonal antibody For blotting immunoprecipitated PDGFR alpha,was used at 1:1000. Chemiluminescence with an exposuretime of 30 seconds.

Applications for PDGFR alpha Antibody (BLR078G)

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

>95%

Formulation

Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 2 - 8 C / 1 year from date of receipt

Background: PDGF R alpha

Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons.

Long Name

Platelet-derived Growth Factor Receptor alpha

Alternate Names

CD140a, PDGFR alpha, PDGFRA

Gene Symbol

PDGFRA

Additional PDGF R alpha Products

Product Documents for PDGFR alpha Antibody (BLR078G)

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Certificate of Analysis

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Product Specific Notices for PDGFR alpha Antibody (BLR078G)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.