Catalog Number: 1598
Biological Activity
Inactive control peptide analog of pep2-SVKI, an inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluR2 AMPA receptor subunit.

Active Analog also available.

Technical Data
  • M.Wt:
    1300.43
  • Formula:
    C59H89N13O20
  • Sequence:
    YNVYGIESVKE
  • Solubility:
    Soluble to 1 mg/ml in 67% acetic acid
  • Storage:
    Desiccate at -20°C
  • CAS No:
    1315378-76-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Interaction of the AMPA receptor subunit GluR2/3 with PDZ domains regulates hippocampal long-term depression.
    Kim et al.
    Proc.Natl.Acad.Sci.U.S.A., 2001;98:11725
  2. AMPA receptor-PDZ interactions in facilitation of spinal sensory synapses.
    Li et al.
    Nat.Neurosci., 1999;2:972
  3. Functional roles of protein interactions with AMPA and kainate receptors.
    Collingridge and Isaac
    Neurosci.Res., 2003;47:3
  4. PDZ proteins interacting with C-terminal GluR2/3 are involved in a PKC-dependent regulation of AMPA receptors at hippocampal synapses.
    Daw et al.
    Neuron, 2000;28:873
Citations:

The citations listed below are publications that use Tocris products. Selected citations for pep2-SVKE include:

1 Citations: Showing 1 - 1

  1. A novel mechanism of hippocampal LTD involving muscarinic receptor-triggered interactions between AMPARs, GRIP and liprin-alpha.
    Authors: Dickinson Et al.
    Mol Brain 2009;2:18

Have you used pep2-SVKE?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

Feedback

Customer Information