Biological ActivityInactive control peptide analog of pep2-SVKI, an inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluA2 AMPA receptor subunit.
Active Analog also available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Functional roles of protein interactions with AMPA and kainate receptors.
Collingridge and Isaac
PDZ proteins interacting with C-terminal GluR2/3 are involved in a PKC-dependent regulation of AMPA receptors at hippocampal synapses.
Daw et al.
Interaction of the AMPA receptor subunit GluR2/3 with PDZ domains regulates hippocampal long-term depression.
Kim et al.
AMPA receptor-PDZ interactions in facilitation of spinal sensory synapses.
Li et al.
Citation for pep2-SVKE
The citations listed below are publications that use Tocris products. Selected citations for pep2-SVKE include:
1 Citation: Showing 1 - 1
A novel mechanism of hippocampal LTD involving muscarinic receptor-triggered interactions between AMPARs, GRIP and liprin-alpha.
Authors: Dickinson Et al.
Mol Brain 2009;2:18
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