PF 4778574

Catalog # Availability Size / Price Qty
4900/10
PF 4778574 | CAS No. 1219633-99-4 | AMPA Receptor Modulators
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Description: Positive allosteric modulator of AMPA receptors

Chemical Name: N-[(3R,4S)-3-[4-(5-cyano-2-thienyl)phenyl]tetrahydro-2H-pyran-4-yl]-2-propanesulfonamide

Purity: ≥98%

Product Details
Reviews

Biological Activity

Positive allosteric modulator of AMPA receptors (Ki = 85 nM). Prevents ketamine-induced working memory impairments. Brain penetrant.

Technical Data

M.Wt:
390.52
Formula:
C19H22N2O3S2
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1219633-99-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Product Datasheets

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