Phaclofen

  ( 2 citations )    
Product Datasheet
Catalog Number:0178
Chemical Name:(RS)-3-Amino-2-(4-chlorophenyl)propylphosphonic acid
Product Details
Citations (2)
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Reviews
Biological Activity
Selective GABAB antagonist. Phosphono analog of GABAB agonist baclofen (Cat. No. 0417).
Technical Data
  • M.Wt:
    249.63
  • Formula:
    C9H13ClNO3P
  • Solubility:
    Soluble to 25 mM in 1eq. NaOH
  • Purity:
    >97
  • Storage:
    Store at RT
  • CAS No:
    114012-12-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Phaclofen include:

2 Citations: Showing 1 - 2
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  1. The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen.
    Authors: Wood Et al.
    Br J Pharmacol  2000;131:1050
  2. Effect of chronic ethanol treatment in vivo on excitability in mouse cortical neurones in vitro.
    Authors: Ibbotson Et al.
    Br J Pharmacol  1997;122:956

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