Catalog Number: 0994
Chemical Name: 1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol
Biological Activity
5-HT1A/1B receptor antagonist, with roughly equal affinity for each subtype. A partial agonist at mouse and human β3-adrenoceptors. (S)-(-)-Pindolol (Cat. No. 1060) also available.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References

  1. Kishimoto T et al.
    Leucocyte Typing VI. Garland Publishing Inc. London.
  2. Structural and conformational features determining selective signal transduction in the β3-adrenergic receptor.
    Blin et al.
    Mol.Pharmacol., 1993;44:1094
  3. Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5-HT1A autoreceptor in vivo.
    Clifford et al.
    Br.J.Pharmacol., 1998;124:206
  4. Antagonist properties of (-)-pindolol and WAY 100635 at somatodendritic and postsynaptic 5-HT1A receptors in the rat brain.
    Corradetti et al.
    Br.J.Pharmacol., 1998;123:449
  5. VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin).
    Hoyer et al.
    Pharmacol.Rev., 1994;46:157

The citations listed below are publications that use Tocris products. Selected citations for Pindolol include:

Showing Results 1 - 2 of 2

  1. Recruitment of β-arrestin 1 and 2 to the β2-adrenoceptor: analysis of 65 ligands.
    Authors: Littmann Et al.
    Front Microbiol
  2. Vasoconstrictor potential of coronary aspirate from patients undergoing stenting of saphenous vein aortocoronary bypass grafts and its pharmacological attenuation.
    Authors: Kleinbongard Et al.
    Circ Res
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