1A/1B receptor antagonist, with roughly equal affinity for each subtype. A partial agonist at mouse and human β 3-adrenoceptors. S-enantiomer also available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Kishimoto T et al.
Leucocyte Typing VI. Garland Publishing Inc. London.
Structural and conformational features determining selective signal transduction in the β 3-adrenergic receptor.
Blin et al.
Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5-HT 1A autoreceptor in vivo.
Clifford et al.
Antagonist properties of (-)-pindolol and WAY 100635 at somatodendritic and postsynaptic 5-HT 1A receptors in the rat brain.
Corradetti et al.
VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin).
Hoyer et al.
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