Piperlongumine

  ( 1 citations )    
Product Datasheet
Catalog Number:4396
Chemical Name:5,6-Dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone
Product Details
Citations (1)
Reviews
Biological Activity
Induces cell death and increases the level of reactive oxygen species (ROS) in cancer cells with both wild-type and normal p53. Also inhibits the growth of spontaneous malignant breast tumors in mice. Displays little effect on normal cells. Rapidly depletes androgen receptor expression in human prostate cancer cells via a ROS-dependent, proteasome-mediated mechanism.
Technical Data
  • M.Wt:
    317.34
  • Formula:
    C17H19NO5
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >97
  • Storage:
    Store at -20°C
  • CAS No:
    20069-09-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Piperlongumine include:

1 Citations: Showing 1 - 1

  1. An improved quantitative approach for the assessment of mitochondrial fragmentation in chemoresistant ovarian cancer cells.
    Authors: Farrand Et al.
    PLoS One  2013;8:e74008

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