Piperlongumine

Catalog # Availability Size / Price Qty
4396/10
4396/50
Piperlongumine | CAS No. 20069-09-4 | Apoptosis Inducer Compounds
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Description: Induces apoptosis; increases p53 and ROS levels in cancer cells

Chemical Name: 5,6-Dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone

Purity: ≥97%

Product Details
Citations (1)
Reviews

Biological Activity

Induces cell death and increases the level of reactive oxygen species (ROS) in cancer cells with both wild-type and normal p53. Also inhibits the growth of spontaneous malignant breast tumors in mice. Displays little effect on normal cells. Rapidly depletes androgen receptor expression in human prostate cancer cells via a ROS-dependent, proteasome-mediated mechanism.

Technical Data

M.Wt:
317.34
Formula:
C17H19NO5
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥97%
Storage:
Store at -20°C
CAS No:
20069-09-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for Piperlongumine

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