PKC gamma Antibody - BSA Free

Name: PKC gamma Antibody - BSA Free
Brand: Novus Biologicals
SKU: NBP3-48269
Price: 279 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-48269

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Mouse, Rat

Applications

Immunohistochemistry, Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

View all PKC gamma Primary Antibodies »

Product Specifications

Immunogen

protein kinase C, gamma. (Uniprot# P63318)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

78 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PKC gamma Antibody - BSA Free

Immunohistochemistry: PKC gamma Antibody - BSA Free [NBP3-48269] -

Immunohistochemistry: PKC gamma Antibody - BSA Free [NBP3-48269] - Immunohistochemistry of paraffin-embedded rat brain tissue slide using (PKC gamma Antibody) at dilution of 1:200

Western Blot: PKC gamma Antibody - BSA Free [NBP3-48269] -

Western Blot: PKC gamma Antibody - BSA Free [NBP3-48269] - Mouse brain tissue were subjected to SDS PAGE followed by western blot with (PKC gamma antibody) at dilution of 1:1000

Applications for PKC gamma Antibody - BSA Free

Application

Recommended Usage

Immunohistochemistry

1:100-1:500

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PKC gamma

Protein Kinase C gamma (PKC gamma) is an 80 kDa member of the conventional group (cPKCs: sensitive to calcium, diacylglycerol, phosphotidylserine and phorbol esters) of the PKC family of serine/threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC gamma plays a key role in neuronal signal transduction and in regulating intercellular communication. The activation loop threonine (threonine 514 in PKC gamma) of conventional PKCs is phosphorylated by phosphoinositide-dependent kinase-1 (PDK1), which is necessary for its autophosphorylation on threonine 655 in the turn loop, and threonine 674 in the hydrophobic loop of the carboxy terminus, a critical step in generating a catalytically mature enzyme. The phosphorylation of the hydrophobic loop in the carboxyl terminus of PKCs is believed to be a key determinant in regulating PKC interaction with PDK1.

Long Name

Protein Kinase C gamma

Alternate Names

PKCC, PKCG, PRKCG, SCA14

Gene Symbol

PRKCG

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Product Specific Notices for PKC gamma Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.