PPT

Tocris Bioscience | Catalog # 1426

Subtype-selective ERα agonist
Tocris Bioscience

Key Product Details

Description

Subtype-selective ERα agonist
View all Estrogen and Related Receptor Agonists »

Product Description

PPT is a potent, subtype-selective estrogen receptor agonist (EC50 ~ 200 pM); displays 410-fold selectivity for ERα over ERβ. Prevents ovariectomy-induced weight gain and loss of bone mineral density, and induces gene expression in the hypothalamus following systemic administration in vivo.

Product Specifications for PPT

Molecular Weight

386.45

Formula

C24H22N2O3

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

4,4',4''-(4-Propyl-[1H]-pyrazole-1,3,5-triyl)trisphenol

CAS Number

263717-53-9

PubChem ID

6095481

InChI Key

UOSWGERPQQOSHS-UHFFFAOYSA-N

SMILES

CCCC1=C(N(N=C1C1=CC=C(O)C=C1)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 38.65 100
Ethanol 1.93 5

Preparing Stock Solutions for PPT

The following data is based on the product molecular weight 386.45.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.59 mL 12.94 mL 25.88 mL
5 mM 0.52 mL 2.59 mL 5.18 mL
10 mM 0.26 mL 1.29 mL 2.59 mL
50 mM 0.05 mL 0.26 mL 0.52 mL

Calculators

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Product Documents for PPT

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PPT

For research use only

Customer Reviews for PPT (1)

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  • Good Product
    Name: Jinan Saboune
    Species: Mouse
    Assay Type: Ex Vivo
    Cell Line/Tissue: CD-1
    Verified Customer | Posted 10/28/2020
    This product was used as an intervention drug with the Langendorff Perfusion System. It was produced at 100nM in ethanol.

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