Catalog Number: 1947
Biological Activity
Antibacterial peptide. Stimulates angiogenesis and inhibits inflammatory responses by selectively blocking proteasome degradation of IκBα.
Technical Data
  • M.Wt:
    4719.7
  • Formula:
    C229H346N70O40
  • Sequence:
    RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP

    (Modifications: Pro-39 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    139637-11-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Inhibition of ubiquitin-proteasome pathway-mediated IκBα degradation by a naturally occuring antibacterial peptide.
    Gao et al.
    J.Clin.Invest., 2000;106:439
  2. Proline and arginine-rich peptides constitute a novel class of allosteric inhibitors of proteasome activity.
    Gaczynska et al.
    Biochemistry, 2003;42:8663
  3. PR39, a peptide regulator of angiogenesis.
    Li et al.
    Nat.Med., 2000;6:356
Citations:

The citations listed below are publications that use Tocris products. Selected citations for PR 39 (porcine) include:

1 Citations: Showing 1 - 1

  1. Stimulation of hepatocarcinogenesis by neutrophils upon induction of oncogenic kras expression in transgenic zebrafish.
    Authors: Yan Et al.
    J Hepatol 2015;63:420

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