Home / Additional Voltage-gated Calcium Channel Compounds / Pregabalin

Pregabalin

3775 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3775/10
3775/50
Additional Voltage-gated Calcium Channel Compounds Small Molecule
1 Image
Description: Anticonvulsant; selectively binds the α2δ subunit of voltage-sensitive calcium channels

Chemical Name: (S)-3-(Aminomethyl)-5-methylhexanoic acid

Product Details
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

Anticonvulsant and antiepileptic; also used to treat neuropathic pain. Binds with high affinity and selectivity to the α2δ subunit of voltage-sensitive Ca2+ channels and modulates their activity. Displays anxiolytic-like activity in ethological and conflict models of anxiety. Analog of GABA (Cat. No. 0344).

Technical Data

M.Wt:
159.23
Formula:
C8H17NO2
Solubility:
Soluble to 100 mM in water
Storage:
Store at RT
CAS No:
148553-50-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Background References

  1. Pregabalin may represent a novel class of anxiolytic agents with a broad spectrum of activity.
    Field et al.
    Br.J.Pharmacol., 2001;132:1
  2. Pregabalin in the management of partial epilepsy.
    Arain
    Neuropsych.Dis.Treat., 2009;5:407
  3. Evidence that prega. reduces neuropathic pain by inhibiting the spinal release of glutamate.
    Kumar et al.
    J.Neurochem., 2010;113:552

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Pregabalin

There are currently no reviews for this product. Be the first to review Pregabalin and earn rewards!

Have you used Pregabalin?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.