Primidone
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Description: Potentiates GABAA receptor function
Chemical Name: 5-Ethyldihydro-5-phenyl-4,6(1H,5H)-pyrimidinedione
Biological Activity
Anticonvulsant.Technical Data
M.Wt:
218.25
Formula:
C12H14N2O2
Solubility:
Soluble to 100 mM in DMSO
Storage:
Store at RT
CAS No:
125-33-7
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Comparison of the anticonvulsant efficacy of PrimiD and phenobarbital during chronic treatment of amygdala-kindled rats.
Loscher and Honack
Eur.J.Pharmacol., 1989;162:309
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⚠ WARNING: This product can expose you to chemicals including Primidone, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov
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