Proteome Profiler Mouse Adipokine Array Kit

Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies
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R&D Systems Proteome Profiler Antibody Array Kits
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Product Details
Citations (19)
Supplemental Products
Reviews (9)

Proteome Profiler Mouse Adipokine Array Kit Summary

Kit Summary

To simultaneously detect the relative levels of 38 different obesity-related molecules in a single sample. No specialized equipment is necessary.

General Assay Principle

Carefully selected capture antibodies have been spotted in duplicate on nitrocellulose membranes. Cell culture supernatant, cell lysate, tissue lysate, or serum samples are diluted and mixed with a cocktail of biotinylated detection antibodies. The sample/antibody mixture is then incubated with the array. Any cytokine/detection antibody complex present is bound by its cognate immobilized capture antibody on the membrane. Streptavidin-Horseradish Peroxidase and chemiluminescent detection reagents are added, and a signal is produced in proportion to the amount of cytokine bound. Chemiluminescence is detected in the same manner as a Western blot.


Kit Contents
  • 4 Array Membranes
  • 4-Well Multi-dish
  • Array Buffers
  • Wash Buffer
  • Detection Antibody Cocktail
  • Streptavidin-HRP
  • Chemiluminescent Detection Reagents
  • Transparency Overlay Template
  • Detailed Protocol

For a complete list of the kit contents and necessary materials, please see the Materials Provided/Materials Required sections of the product datasheet.

Stability and Storage

Store the unopened kit at 2 °C to 8 °C. Do not use past kit expiration date.


Simultaneously detect the levels of these obesity-related proteins in a single sample.
Adiponectin IGF-I M-CSF
ANGPT-L3 IGFBP-1 PAI-1/Serpin E1
CRP IGFBP-5 Pref-1
Endocan IL-6 RBP4
Fetuin A IL-10 Resistin
FGF acidic IL-11 TIMP-1
FGF-21 Leptin TNF-alpha
ICAM-1 Lipocalin-2/NGAL  


Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Product Datasheets

Citations for Proteome Profiler Mouse Adipokine Array Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

19 Citations: Showing 1 - 10
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  1. Obesity alters ovarian folliculogenesis through disrupted angiogenesis from increased IL-10 production
    Authors: PK Yang, CH Chou, CC Huang, WF Wen, HF Chen, CT Shun, HN Ho, MJ Chen
    Molecular Metabolism, 2021;49(0):101189.  2021
  2. Pineapple Vinegar Regulates Obesity-Related Genes and Alters the Gut Microbiota in High-Fat Diet (HFD) C57BL/6 Obese Mice
    Authors: NE Mohamad, SK Yeap, H Ky, NWC Liew, BK Beh, SY Boo, WY Ho, SA Sharifuddi, K Long, NB Alitheen
    Evid Based Complement Alternat Med, 2020;2020(0):1257962.  2020
  3. Glucose transporter 10 modulates adipogenesis via an ascorbic acid-mediated pathway to protect mice against diet-induced metabolic dysregulation
    Authors: CL Jiang, WP Jen, CY Tsao, LC Chang, CH Chen, YC Lee
    PLoS Genet., 2020;16(5):e1008823.  2020
  4. Functional expression of TRPM7 as a Ca2+ influx pathway in adipocytes
    Authors: H Inoue, M Inazu, M Konishi, U Yokoyama
    Physiol Rep, 2019;7(20):e14272.  2019
  5. Immune-Deficient Pfp/Rag2-/- Mice Featured Higher Adipose Tissue Mass and Liver Lipid Accumulation with Growing Age than Wildtype C57BL/6N Mice
    Authors: S Winkler, M Hempel, MJ Hsu, M Gericke, H Kühne, S Brückner, S Erler, R Burkhardt, B Christ
    Cells, 2019;8(8):.  2019
  6. Early postnatal soluble FGFR3 therapy prevents the atypical development of obesity in achondroplasia
    Authors: C Saint-Laur, S Garcia, V Sarrazy, K Dumas, F Authier, S Sore, A Tran, P Gual, I Gennero, JP Salles, E Gouze
    PLoS ONE, 2018;13(4):e0195876.  2018
  7. Insulin resistance causes inflammation in adipose tissue
    Authors: M Shimobayas, V Albert, B Woelnerhan, IC Frei, D Weissenber, AC Meyer-Gers, N Clement, S Moes, M Colombi, JA Meier, MM Swierczyns, P Jenö, C Beglinger, R Peterli, MN Hall
    J. Clin. Invest., 2018;0(0):.  2018
  8. Potential Hypoglycaemic and Antiobesity Effects of Senna italica Leaf Acetone Extract
    Authors: RO Malematja, VP Bagla, I Njanje, V Mbazima, KW Poopedi, L Mampuru, MP Mokgotho
    Evid Based Complement Alternat Med, 2018;2018(0):5101656.  2018
  9. Adipose tissue supports normalization of macrophage and liver lipid handling in obesity reversal
    Authors: M Vatarescu, S Bechor, Y Haim, T Pecht, T Tarnovsky, N Slutsky, O Nov, H Shapiro, A Shemesh, A Porgador, N Bashan, A Rudich
    J. Endocrinol., 2017;0(0):.  2017
  10. Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment
    Authors: S Gomez-Chou, A Swidnicka-, N Badi, M Chavez-Tom, GB Lesinski, T Bekaii-Saa, MR Farren, TA Mace, C Schmidt, Y Liu, D Deng, RF Hwang, L Zhou, TT Moore, D Chatterjee, H Wang, X Leng, RB Arlinghaus, CD Logsdon, Z Cruz-Monse
    Cancer Res, 2017;0(0):.  2017
  11. Mfn2 is critical for brown adipose tissue thermogenic function
    Authors: M Boutant, SS Kulkarni, M Joffraud, J Ratajczak, M Valera-Alb, R Combe, A Zorzano, C Cantó
    EMBO J, 2017;0(0):.  2017
  12. Alterations in Adiposity and Glucose Homeostasis in Adult Gasp-1 Overexpressing Mice
    Authors: L Périè, A Parenté, F Baraige, L Magnol, V Blanquet
    Cell. Physiol. Biochem., 2017;44(5):1896-1911.  2017
  13. High-fat Diet Enhances Mammary Tumorigenesis and Pulmonary Metastasis and Alters Inflammatory and Angiogenic Profiles in MMTV-PyMT Mice
    Authors: Sneha Sundaram
    Anticancer Res, 2016;36(12):6279-6287.  2016
  14. Hsp90 blockers inhibit adipocyte differentiation and fat mass accumulation.
    Authors: Desarzens S, Liao W, Mammi C, Caprio M, Faresse N
    PLoS ONE, 2014;9(4):e94127.  2014
  15. Leucine-rich glioma inactivated 3 associates negatively with adiponectin.
    Authors: Kim H, Kwon N, Baek K, Kim D, Yun H
    Cytokine, 2013;62(2):206-9.  2013
  16. Obesity-related systemic factors promote an invasive phenotype in prostate cancer cells.
    Authors: Price RS, Cavazos DA, De Angel RE, Hursting SD, Degraffenried LA
    Prostate Cancer Prostatic Dis., 2012;15(2):135-43.  2012
  17. Efficacy and tolerability of a novel herbal formulation for weight management in obese subjects: a randomized double blind placebo controlled clinical study.
    Authors: Sengupta K, Mishra A, Rao M, Sarma K, Krishnaraju A, Trimurtulu G
    Lipids Health Dis, 2012;11(0):122.  2012
  18. Palmitate enhances the differentiation of mouse embryonic stem cells towards white adipocyte lineages.
    Authors: Petrighi Polidori G, Lomax M, Docherty K
    Mol Cell Endocrinol, 2012;361(1):40-50.  2012
  19. Age and sex mediated changes in epicardial fat adipokines.
    Authors: Fei J, Cook C, Blough E, Santanam N
    Atherosclerosis, 2010;212(2):488-94.  2010


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Reviews for Proteome Profiler Mouse Adipokine Array Kit

Average Rating: 4.9 (Based on 9 Reviews)

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Proteome Profiler Mouse Adipokine Array Kit
By Anonymous on 02/19/2021

Consistent resuts.

Proteome Profiler Mouse Adipokine Array Kit
By Anonymous on 02/17/2021

Phenomenal kit that is easy to use and reliable.

Proteome Profiler Mouse Adipokine Array Kit
By Anonymous on 02/10/2021

Outstanding kit.

Proteome Profiler Mouse Adipokine Array Kit
By Anonymous on 06/04/2019

We evaluated the adipokine profile of two different mice's groups: a high fat diet and a control group fed with a pigment. We observed significant changes in several proteins

Proteome Profiler Mouse Adipokine Array Kit
By Anonymous on 04/30/2019

Proteome Profiler Mouse Adipokine Array Kit
By Anonymous on 12/11/2018

Proteome Profiler Mouse Adipokine Array Kit
By Anonymous on 11/13/2018

Tested in 3T3-L1 cells, data matches expectation, very good

Proteome Profiler Mouse Adipokine Array Kit
By Anonymous on 10/19/2017

Proteome Profiler Mouse Adipokine Array Kit
By Anonymous on 10/06/2016