PSB 0474

  ( 5 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:2715
Alternate Names:3-Phenacyl UDP disodium salt
Chemical Name:3-(2-Oxo-2-phenylethyl)-uridine-5'-diphosphate disodium salt
Product Details
Citations (5)
Supplemental Products
Reviews
Biological Activity
Potent and selective P2Y6 receptor agonist (EC50 values are 70, > 1000 and > 10000 nM for P2Y6, P2Y2 and P2Y4 receptors respectively). Induces contractions of rat isolated intrapulmonary arteries in vitro.
Technical Data
  • M.Wt:
    566.26
  • Formula:
    C17H18N2Na2O13P2
  • Solubility:
    Soluble in water (supplied pre-dissolved at a concentration of 10mM)
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    917567-60-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for PSB 0474 include:

5 Citations: Showing 1 - 5
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  1. Activation of P2Y6 receptors increases the voiding frequency in anaesthetized rats by releasing ATP from the bladder urothelium.
    Authors: Carneiro Et al.
    Br J Pharmacol  2014;171:3404
  2. Microglia P2Y6 receptors mediate nitric oxide release and astrocyte apoptosis.
    Authors: Quintas Et al.
    J Neuroinflammation  2014;11:141
  3. Role of spinal P2Y6 and P2Y11 receptors in neuropathic pain in rats: possible involvement of glial cells.
    Authors: Barragán-Iglesias Et al.
    Mol Pain  2014;10:29
  4. The role of P2Y(14) and other P2Y receptors in degranulation of human LAD2 mast cells.
    Authors: Gao Et al.
    Exp Eye Res  2013;9:31
  5. Involvement of vasodilator-stimulated phosphoprotein in UDP-induced microglial actin aggregation via PKC- and Rho-dependent pathways.
    Authors: Kataoka Et al.
    Purinergic Signal  2011;7:403

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Average Rating: 4 (Based on 1 review)

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