The selection and quality of our blocking/neutralizing antibodies is unparalleled. Our commitment to quality allows you to be confident in your results and help you generate publication-quality data. Details regarding the steps we take to provide you with only the highest-quality antibodies are listed below.
We offer over 1,200 antibodies that have been validated for blocking/neutralizing.
We utilize our selection of in-house manufactured proteins and our bioassay expertise to ensure that our antibodies block/neutralize the appropriate cellular function. Our assays include proliferation, chemotaxis, protein secretion, adhesion, and in vitro enzyme neutralization. We continuously add new assays to ensure the highest specificity based on the latest research data.
Our neutralizing antibodies are manufactured to ensure low endotoxin levels. Each lot is QC tested for the level of endotoxin and the information is reported on each individual datasheet. You won’t have to worry about endotoxin-induced nonspecific cellular responses.
What’s the difference between blocking and neutralizing? A blocking antibody binds its target and directly interferes with its function, such as blocking cell adhesion or receptor-ligand binding. A neutralizing antibody binds its target and negates its downstream cellular effects, such as cell proliferation or chemotaxis.