Catalog Number: 0630
Chemical Name: [R-(+)]-α-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxybenzenepropanoic acid
Biological Activity
Anti-inflammatory, cytostatic and antiviral. Also displays agonist activity at GPR35.
Technical Data
  • M.Wt:
    360.32
  • Formula:
    C18H16O8
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    20283-92-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Rosmarinic acid inhibits external oxidative effects of human polymorphonuclear granulocytes.
    Van Kessel et al.
    Agents Actions., 1986;17:375
  2. Modification of endotoxin-induced haemodynamic and haematological changes in the rabbit by methylprednisolone, F(ab')2 fragments and rosmarinic acid.
    Bult et al.
    Br.J.Pharmacol., 1985;84:317
  3. Inhibition of complement by covalent attachment of rosmarinic acid to activated C3b.
    Sahu et al.
    Biochem.Pharmacol., 1999;57:1439
  4. Complement-dependent stimulation of prostacyclin biosynthesis: inhibition by rosmarinic acid.
    Rampart et al.
    Biochem.Pharmacol., 1986;35:1397
  5. Multiple tyrosine metabolites are GPR35 agonists.
    Deng et al.
    Sci.Rep., 2012;2:373

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