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SEN 1269

Catalog #: 4699 Datasheet / COA / SDS

Discontinued Product

4699 has been discontinued.
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SEN 1269 | CAS No. 956128-01-1 | Amyloid beta Peptide Inhibitors
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Description: Amyloid-β aggregation inhibitor

Chemical Name: 3-[[5-[3-(Dimethylamino)phenoxy]-2-pyrimidinyl]amino]phenol

Purity: ≥98%

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Biological Activity

Amyloid-β (Aβ) aggregation inhibitor; blocks Aβ(1-42) aggregation and protects neuronal cell lines exposed to Aβ(1-42). Reduces Aβ oligomer-induced LTP and memory deficits in vivo.

Technical Data

M.Wt:
322.36
Formula:
C18H18N4O2
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
956128-01-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Aβ oligomer toxicity inhibitor protects memory in models of synaptic toxicity.
    Scopes et al.
    Br.J.Pharmacol., 2012;167:383

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