SIB 1757

  ( 1 citations )    
Product Datasheet
Catalog Number:1215
Chemical Name:6-Methyl-2-(phenylazo)-3-pyridinol
Product Details
Citations (1)
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Biological Activity
A highly selective antagonist for the mGlu5 metabotropic glutamate receptor subtype; displays an IC50 value of 0.4 μM at hmGlu5 compared with > 30 μM at hmGlu1b, hmGlu2, hmGlu4, hmGlu6, hmGlu7 and hmGlu8.
Technical Data
  • M.Wt:
    213.24
  • Formula:
    C12H11N3O
  • Solubility:
    Soluble to 100 mM in DMSO
  • Storage:
    Store at RT
  • CAS No:
    31993-01-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for SIB 1757 include:

1 Citations: Showing 1 - 1

  1. Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A-841720, a novel non-competitive mGluR1 receptor antagonist.
    Authors: El-Kouhen Et al.
    Br J Pharmacol  2006;149:761

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