SNX27 Antibody [FITC]

Novus Biologicals | Catalog # NBP1-45282F

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Bovine (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry/ Immunofluorescence

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Polyclonal Rabbit IgG
View all SNX27 Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide made to an internal portion of human SNX27 (within residues 150-200). [Swiss-Prot# Q96L92]

Reactivity Notes

Immunogen sequence has 94% identity to rat and bovine.

Localization

Cytoplasm cytosol. Early endosome. Note: In T lymphocytes, recruited from the cytosol to sorting endosomes by phosphoinositide-3-kinase products.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for SNX27 Antibody [FITC]

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: SNX27

SNX27 belongs to SNX family of proteins which are unified by the presence of a phox domain, a phospholipid-binding motif, and are involved in intracellular sorting as well as trafficking. SNX27 was initially discovered in neocortex of rat as a developmentally regulated psychostimulant-inducible novel gene, which was named mrt1 (methamphetamine-responsive transcript 1), having two splice forms mrt1a (SNX27a) and mrt1b (SNX27b) that vary only in their C-terminal ends. In SNX family, SNX27 is the only SNX member containing a PDZ domain and it interact with the PDZ-bm of a few membrane proteins through its PDZ domain to regulate their intracellular sorting. SNX27 modulates the early endosomal trafficking of 5-HT4(a)R [5-hydroxytryptamine type-4(a) receptor], Kir3 (G protein-gated potassium) channels, NR2C (N-methyl-D-aspartate receptor 2C) etc., and has also been suggested to facilitate efficient recycling of beta2AR/beta2-adrenoreceptor to the plasma membranes.

Alternate Names

KIAA0488MGC126873, methamphetamine-responsive transcript 1, MGC126871, MGC20471, MRT1, MY014, sorting nexin family member 27, sorting nexin-27

Gene Symbol

SNX27

Additional SNX27 Products

Product Documents for SNX27 Antibody [FITC]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for SNX27 Antibody [FITC]

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for SNX27 Antibody [FITC]

There are currently no reviews for this product. Be the first to review SNX27 Antibody [FITC] and earn rewards!

Have you used SNX27 Antibody [FITC]?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies