The most abundant peptide neurotransmitter in the mammalian CNS. A weak activator of NMDA receptors, and a highly selective agonist for mGlu3
receptors. Neuroprotective under non-hydrolysing conditions in vivo
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N-Acetylated α-linked acidic dipeptidase converts N-acetylaspartylglutamate from a neuroprotectant to a neurotoxin.
Thomas et al.
N-Acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells.
Wroblewska et al.
N-Acetylaspartylglutamate: the most abundant peptide neurotransmitter in the mammalian central nervous system.
Neale et al.
The citations listed below are publications that use Tocris products. Selected citations for Spaglumic acid include:
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