SR-AI/MSR Antibody (10O8B0)

Novus Biologicals | Catalog # NBP3-16126

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Validated by

Biological Validation

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 10O8B0 expressed in HEK293
View all SR-AI/MSR Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SR-AI/MSR (P21757). MEQWDHFHNQQEDTDSCSESVKFDARSMTALLPPNPKNSPSLQEKLKSFKAALIALYLLVFAVLIPLIGIVAAQLLKWETKNCSVSSTNANDITQSLTGK

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SR-AI/MSR Antibody (10O8B0)

Western Blot: SR-AI/MSR Antibody (10O8B0) [NBP3-16126]

Western Blot: SR-AI/MSR Antibody (10O8B0) [NBP3-16126]

Western Blot: SR-AI/MSR Antibody (10O8B0) [NBP3-16126] - Western blot analysis of extracts of various cell lines, using SR-AI/MSR antibody (NBP3-16126) at 1:1000 dilution.C6 cells were treated by LPS for 6 hours and Brefeldin A for 3 hours of stimulation. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Immunohistochemistry-Paraffin: SR-AI/MSR Antibody (10O8B0) [NBP3-16126]

Immunohistochemistry-Paraffin: SR-AI/MSR Antibody (10O8B0) [NBP3-16126]

Immunohistochemistry-Paraffin: SR-AI/MSR Antibody (10O8B0) [NBP3-16126] - Immunohistochemistry of paraffin-embedded mouse testis using SR-AI/MSR Rabbit mAb (NBP3-16126) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Immunohistochemistry-Paraffin: SR-AI/MSR Antibody (10O8B0) [NBP3-16126]

Immunohistochemistry-Paraffin: SR-AI/MSR Antibody (10O8B0) [NBP3-16126]

Immunohistochemistry-Paraffin: SR-AI/MSR Antibody (10O8B0) [NBP3-16126] - Immunohistochemistry of paraffin-embedded rat brain using SR-AI/MSR Rabbit mAb (NBP3-16126) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

Applications for SR-AI/MSR Antibody (10O8B0)

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Western Blot

1:500 - 1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol, 0.05% BSA

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SR-AI/MSR

Macrophage scavenger receptors (MSR) are membrane glycoproteins that mediate the recognition and uptake of a variety of macromolecules, including modified lipoproteins, advanced glycation end (AGEs) products and amyloid b-protein (Abeta). While the normal role of MSR is associated with cell adhesion and host defense mechanisms, it also has been implicated in the development of atherosclerosis and Abeta deposition in Alzheimer's disease (AD).

In cell cultures, macrophage scavenger receptor has been shown to mediate adhesion of macrophages and other cell lines to tissue culture plastic. MSR1 antibodies are useful for research on atherosclerosis, Alzheimer's disease, and host defense.

Long Name

Macrophage Scavenger Receptor Types I and II

Alternate Names

CD204, MSR1, SCARA1, SRAI

Gene Symbol

MSR1

Additional SR-AI/MSR Products

Product Documents for SR-AI/MSR Antibody (10O8B0)

Certificate of Analysis

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Product Specific Notices for SR-AI/MSR Antibody (10O8B0)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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Associated Pathways

A-beta Pathways: Uptake & Degradation A-beta Pathways: Uptake & Degradation Thumbnail