Chemical Name: 1-[(2R,5S)-2,5-Dihydro-5-(hydroxymethyl)-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
Biological ActivityNucleoside analog; antiviral that inhibits HIV replication in vitro. Orally bioavailable.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro.
Baba et al.
Antiretroviral activity of stavudine (2',3'-didehydro-3'-deoxythymidine, D4T).
Riddler et al.
Antiviral Res., 1995;27:189
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