High affinity BET bromodomain ligand (Kd
values are 40 and 800 nM for Brd2(2) and Brd2(1), respectively). Exhibits 20-fold selectively for the second over the first bromodomain.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold under licence from the University of Dundee.
New synthetic routes to triazolo-benzodiazepine analogues: expanding the scope of the bump-and-hole approach for selective bromo and extra-terminal (BET) bromodomain inhibition.
Baud et al.