Potent GPR139 agonist (EC50
= 39 nM in CHO-K1 cells expressing human GPR139). Displays no activity against a range of 90 diverse targets.
Soluble to 50 mM in DMSO
Store at +4°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Discovery and SAR of a series of agonists at orphan G protein-coupled receptor 139.
Shi et al.
ACS Med.Chem.Lett., 2011;2:303