Chemical Name: 3,5-Dimethoxybenzoic acid 2-[(1-naphthalenylamino)carbonyl]hydrazide
Biological ActivityPotent GPR139 agonist (EC50 = 39 nM in CHO-K1 cells expressing human GPR139). Displays no activity against a range of 90 diverse targets.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Discovery and SAR of a series of agonists at orphan G protein-coupled receptor 139.
Shi et al.
ACS Med.Chem.Lett., 2011;2:303
Citation for TC-O 9311
The citations listed below are publications that use Tocris products. Selected citations for TC-O 9311 include:
1 Citation: Showing 1 - 1
Re-evaluation of Adrenocorticotropic Hormone and Melanocyte Stimulating Hormone Activation of GPR139 in Vitro.
Authors: Nepomuceno Et al.
Front Pharmacol 2018;9:157
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