Selective inhibitor of Na+
channel conductance. Binding is reversible and of high affinity (Kd
= 1-10 nM). Blocks in a use-dependent manner.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Kishimoto T et al.
Leucocyte Typing VI. Garland Publishing Inc. London.
The protective action of tetrodotoxin and (±)-kavain on anaerobic glycolysis, ATP content and intracellular Na+ and Ca2+ of anoxic brain vesicles.
Gleitz et al.
Pharmacology of tetrodotoxin and saxitoxin.
Structure-activity relations of tetrodotoxin, saxitoxin, and analogues.
The citations listed below are publications that use Tocris products. Selected citations for Tetrodotoxin include:
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