TGF-beta 2 Antibody [HRP]

Name: TGF-beta 2 Antibody [HRP]
Brand: Novus Biologicals
SKU: AF-302-NAH
Price: 569 USD
Availability: InStock

Novus Biologicals | Catalog # AF-302-NAH

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Multi-Species

Applications

Western Blot, Neutralization

Label

HRP

Antibody Source

Polyclonal Goat IgG

View all TGF-beta 2 Primary Antibodies »

Product Specifications

Immunogen

Porcine platelet-derived TGF-beta 2

Specificity

Detects TGF‑ beta 2 in direct ELISAs and Western blots. In direct ELISAs and Western blots (non-reducing conditions), less than 2% cross‑reactivity with TGF-beta 1, TGF-beta 3, and TGF-beta 5 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for TGF-beta 2 Antibody [HRP]

Application

Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Neutralization

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TGF-beta 2

Transforming Growth Factor (TGF) betas mediate many cell to cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide. TGF beta 1, TGF beta 2, and TGF beta 1.2 appear to be equivalent in biological activity, although there does appear to be differences in binding to certain types of receptors. TGF beta 2 is produced by many cell types and has been found in the highest concentration in porcine platelets and mammalian bone. Latent TGF beta 2 is the prominent isoform found in body fluids such as amniotic fluid, breast milk, and the aqueous and vitreous humor of the eye.

Long Name

Transforming Growth Factor beta 2

Alternate Names

TGFB2, TGFbeta 2

Additional TGF-beta 2 Products

Product Documents for TGF-beta 2 Antibody [HRP]

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Certificate of Analysis

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Product Specific Notices for TGF-beta 2 Antibody [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.