THEM6 Antibody - BSA Free

Immunohistochemistry-Paraffin: THEM6 Antibody [NBP1-84052]

Immunohistochemistry-Paraffin: THEM6 Antibody [NBP1-84052] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.

Immunohistochemistry-Paraffin: THEM6 Antibody [NBP1-84052]

Immunohistochemistry-Paraffin: THEM6 Antibody [NBP1-84052] - Staining of human Fallopian tube shows moderate to strong membranous positivity in glandular cells.

Immunohistochemistry-Paraffin: THEM6 Antibody [NBP1-84052]

Immunohistochemistry-Paraffin: THEM6 Antibody [NBP1-84052] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

Immunohistochemistry: THEM6 Antibody - BSA Free [NBP1-84052] -

Xiangya cohort validates the relationship between THEM6 and immune phenotypes. (a) Exome sequencing analysis on THEM6 mRNA levels in 12 paired bladder cancer and normal tissues. (b) QPCR estimation on three cancer cell lines (T24, J82, and 5637) and one normal cell line (SV-HUC-1). The asterisks indicate a significant statistical P value calculated using paired-samples t-test. (c) Expression of THEM6, PD-L1, and CD8 in the BLCA TMA cohort was detected using immunohistochemistry. Representative images of CD8, PD-L1, and THEM6 in three immune phenotypes were displayed. The scale bars correspond to 200 μm. (d) CD8-positive rates in the three immune phenotypes in the BLCA TMA cohort detected by IHC. (e) Correlation between PD-L1-positive rates and CD8-positive rates detected using IHC. (f, g) Correlation between THEM6-positive rates and CD8/PD-L1-positive rates detected using IHC, respectively. The asterisks indicate a significant statistical P value calculated using the Mann–Whitney U test (∗P < 0.05; ∗∗P < 0.01; ∗∗∗P < 0.001). (h) Correlations between THEM6 and the steps of the cancer immunity cycle. (i) Correlations between THEM6 and four critical marker genes of macrophages. (j) Correlations between THEM6 and 20 immune checkpoints. The color and the values indicate the Spearman correlation coefficient. IHC: immunohistochemistry. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/35909893), licensed under a CC-BY license. Not internally tested by Novus Biologicals.