Home / Smoothened Receptor Agonists / Purmorphamine

Purmorphamine

4551 2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4551/10
4551/50
Cat.No. 4551 - Purmorphamine | C31H32N6O2 | CAS No. 483367-10-8
1 Image
Description: Smo receptor agonist

Chemical Name: 9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine

Purity: ≥98%

Product Details
Citations (2)
Supplemental Products
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Smoothened (Smo) receptor agonist (EC50 ~ 1 μM). Induces osteogenesis in mouse mesenchymal progenitor cells (C3H10T1/2). When combined with BMP-4, can transdifferentiate pre-adipocytes (3T3-L1) and myoblasts (C2C12) into osteoblasts. Induces differentiation of multipotent mesenchymal progenitor cells into osteoblasts.

Technical Data

M.Wt:
520.62
Formula:
C31H32N6O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
483367-10-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Product Datasheets

COA view current batch
or select another batch:
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for Purmorphamine

The citations listed below are publications that use Tocris products. Selected citations for Purmorphamine include:

2 Citations: Showing 1 - 2

  1. Th17 lymphocytes induce neuronal cell death in a human iPSC-based model of Parkinson's disease.
    Authors: Sommer Et al.
    Cell Stem Cell.  2018;23:123
  2. Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation.
    Authors: Yuan Et al.
    J Immunol  2016;7:11024

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

VersaClone cDNA Plasmids

Human Smoothened (NP_005622) VersaClone cDNA

RDC2144

Reviews for Purmorphamine

There are currently no reviews for this product. Be the first to review Purmorphamine and earn rewards!

Have you used Purmorphamine?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.