Catalog Number: 4152
Chemical Name: 2-Chloro-N-[(9H-fluoren-9-ylamino)carbonyl]-6-fluorobenzamide
Biological Activity
Potent cyclophilin A inhibitor (IC50 = 1.52 nM). Approximately 27 times more potent than cyclosporin A (Cat. No. 1101).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 40 mM in DMSO
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Discovering potent small molecule inhibitors of cyclophilin A using de novo drug design approach.
    Ni et al.
    J.Med.Chem., 2009;52:5295

The citations listed below are publications that use Tocris products. Selected citations for TMN 355 include:

Showing Results 1 - 1 of 1

  1. Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities
    Authors: Ahmed-Belkacem Et al.
    Nature Communications
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