TMN 355
Chemical Name: 2-Chloro-N-[(9H-fluoren-9-ylamino)carbonyl]-6-fluorobenzamide
Purity: ≥98%
Biological Activity
TMN 355 is a potent cyclophilin A inhibitor (IC50 = 1.52 nM). Approximately 27 times more potent than cyclosporin A (Cat. No. 1101).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Background References
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Discovering potent small molecule inhibitors of cyclophilin A using de novo drug design approach.
Ni et al.
J.Med.Chem., 2009;52:5295
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Citations for TMN 355
The citations listed below are publications that use Tocris products. Selected citations for TMN 355 include:
2 Citations: Showing 1 - 2
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Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities
Authors: Ahmed-Belkacem Et al.
Nature Communications 2016;7:12777
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Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities.
Authors: Ahmed-Belkacem Et al.
Nature Communications 2016;7:12777
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