TMN 355

Catalog # Availability Size / Price Qty
4152/10
4152/50
Miscellaneous Compounds Small Molecule
1 Image
Description: Cyclophilin A inhibitor

Chemical Name: 2-Chloro-N-[(9H-fluoren-9-ylamino)carbonyl]-6-fluorobenzamide

Purity: ≥98%

Product Details
Citations (2)
Reviews (1)

Biological Activity

Potent cyclophilin A inhibitor (IC50 = 1.52 nM). Approximately 27 times more potent than cyclosporin A (Cat. No. 1101).

Technical Data

M.Wt:
380.8
Formula:
C21H14ClFN2O2
Solubility:
Soluble to 40 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
1186372-20-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for TMN 355

The citations listed below are publications that use Tocris products. Selected citations for TMN 355 include:

2 Citations: Showing 1 - 2

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We used TMN 355 to inhibit response for our study
By Anonymous on 02/20/2019
Species: Human

Cyclophilin A is secreted from these monocytes, endothelial cells and vascular smooth muscle cells in response to inflammatory stimuli such as hyperglycemia, hypoxia, infection and oxidative stress.We used TMN 355 to inhibit such response for our study.


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