Chemical Name: 2,2,6,6-Tetramethylpiperidin-4-yl heptanoate
Biological Activity Potent non-competitive antagonist of neuronal nicotinic ACh receptors (nAChRs). Produces long-lasting inhibition of neuronal nAChRs formed by the combination of the most abundant α and β subunits (i.e. α3, α4 and β2, β4 respectively). Displays little inhibition of muscle-type (α1β1γδ) or α7 receptors.
Soluble to 100 mM in water and to 100 mM in DMSO
Desiccate at RT
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