Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all TRAF-3 Primary Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human. The immunogen is located within amino acids 20 - 70 of TRAF3. Amino Acid Squence: GYKEKFVKTVEDKYK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TRAF-3 Antibody - BSA Free

Western Blot: TRAF-3 AntibodyBSA Free [NBP1-76642]

Western Blot: TRAF-3 AntibodyBSA Free [NBP1-76642]

Western Blot: TRAF-3 Antibody [NBP1-76642] - HeLa cell lysate with TRAF3 antibody at (A) 2 and (B) 4 ug/ml.
TRAF-3 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: TRAF-3 Antibody - BSA Free [NBP1-76642] -

Immunocytochemistry/ Immunofluorescence: TRAF-3 Antibody - BSA Free [NBP1-76642] - Immunocytochemistry of TRAF-3 in HeLa cells with TRAF-3 antibody at 10 ug/mL.

Applications for TRAF-3 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

10 ug/ml

Western Blot

2-4 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAF-3

Tumor necrosis factor (TNF) receptor associated factors (TRAFs) are the major signal transducers for the TNF receptor superfamily and the interleukin-1 receptor/Toll-like receptor (IL-1/TLR) superfamily. TRAF3 was first identified by its interaction with CD40 and the Epstein-Barr virus transforming protein LMP1. Several TRAF3 mRNA splice variants exist and some of these can activate the transcription factor NF-kappaB. Besides CD40, TRAF3 also interacts with the TRFR superfamily member lymphotoxin-beta receptor (LTbetaR) in association with TRAF2 and the apoptosis inhibitors cIAP1 and Smac. It has been suggested that TRAF3 induces mitochondria-mediated apoptosis upon binding of the TNF family cytokine LIGHT by LTbetaR.

Long Name

TNF Receptor-Associated Factor 3

Alternate Names

CAP1, CD40bp, CRAF1, LAP1, TRAF3

Gene Symbol

TRAF3

UniProt

NP_663777 (Human)

Additional TRAF-3 Products

Product Documents for TRAF-3 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for TRAF-3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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