TW 37

   
Product Datasheet
Catalog Number:4038
Chemical Name:N-[4-[[2-(1,1-Dimethylethyl)phenyl]sulfonyl]phenyl]-2,3,4-trihydroxy-5-[[2-(1-methylethyl)phenyl]methyl]benzamide
Product Details
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Biological Activity
Bcl-2 inhibitor (Ki values are 0.29 μM and 1.11 μM for Bcl-2 and Bcl-XL respectively). Inhibits the angiogenic potential of endothelial cells in vitro. Induces S-phase arrest and apoptosis in pancreatic cancer cell lines; also inhibits the activation of Notch-1 and Jagged-1 in vitro and in vivo.
Technical Data
  • M.Wt:
    573.7
  • Formula:
    C33H35NO6S
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >97
  • Storage:
    Store at -20°C
  • CAS No:
    877877-35-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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