U 99194 maleate

Key Product Details

Product Description

U 99194 maleate is a potent, selective D₃ antagonist. K_i values are 160, 2281 and > 10000 nM for human cloned D₃, D₂ and D₄ receptors respectively.

Product Specifications for U 99194 maleate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for U 99194 maleate

The following data is based on the product molecular weight 393.48.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	10.17 mL	50.83 mL	101.66 mL
1.25 mM	2.03 mL	10.17 mL	20.33 mL
2.5 mM	1.02 mL	5.08 mL	10.17 mL
12.5 mM	0.20 mL	1.02 mL	2.03 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 7 publications citing the usage of this product.

• Clifford and Waddington Heterogeneity of behavioural profile between three putative selective D₃ DA receptor antagonists using an ethologically based approach. Psychopharmacology 1998 PMID: 9566814
• LaHoste DA D₁ receptors synergize with D₂, but not D₃ or D₄, receptors in the striatum without the involvement of action potentials. J.Neurosci. 2000 PMID: 10964971
• Audinot A comparative in vitro and in vivo pharmacological characterization of the novel DA D₃ receptor antagonists (+)-S 14297, nafadotride, GR 103,691 and U 99194. J.Pharmacol.Exp.Ther. 1998 PMID: 9765337

Product Documents for U 99194 maleate