U 99194 maleate
Chemical Name: 2,3-Dihydro-5,6-dimethoxy-N, N-dipropyl-1H-inden-2-amine maleate
Biological ActivityU 99194 maleate is a potent, selective D3 antagonist. Ki values are 160, 2281 and > 10000 nM for human cloned D3, D2 and D4 receptors respectively.
The technical data provided above is for guidance only.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Heterogeneity of behavioural profile between three putative selective D3 DA receptor antagonists using an ethologically based approach.
Clifford and Waddington
A comparative in vitro and in vivo pharmacological characterization of the novel DA D3 receptor antagonists (+)-S 14297, nafadotride, GR 103,691 and U 99194.
Audinot et al.
DA D1 receptors synergize with D2, but not D3 or D4, receptors in the striatum without the involvement of action potentials.
LaHoste et al.
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