UBP 296

  ( 1 citations )    
Product Datasheet
Catalog Number:2078
Chemical Name:(RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione
Product Details
Citations (1)
Supplemental Products
Reviews
Biological Activity
Selective GluK1 (formally GluR5) subunit containing kainate receptor antagonist (apparent KD = 1.09 μM). Displays ~ 90-fold selectivity over AMPA receptors and recombinant hGluK2 (formally hGluR6) and GluK5 (formally KA2) containing kainate receptors. Has little or no action at NMDA or group I mGlu receptors. Selectively blocks kainate receptor-mediated LTP induction in rat hippocampal mossy fibers.

Active Enantiomer also available.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Technical Data
  • M.Wt:
    333.3
  • Formula:
    C15H15N3O6
  • Solubility:
    Soluble to 10 mM in 1eq. NaOH with gentle warming and to 10 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    745055-86-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for UBP 296 include:

1 Citations: Showing 1 - 1

  1. Chondroitin Sulfate Induces Depression of Synaptic Transmission and Modulation of Neuronal Plasticity in Rat Hippocampal Slices.
    Authors: Albiñana Et al.
    Neural Plast  2015;2015:463854

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Have you used UBP 296?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee