UBR1 Antibody

Novus Biologicals | Catalog # NBP3-12361

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit
View all UBR1 Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide taken within amino acid region 1260-1500 on human UBR1 protein.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for UBR1 Antibody

Western Blot: UBR1 Antibody [NBP3-12361]

Western Blot: UBR1 Antibody [NBP3-12361]

Western Blot: UBR1 Antibody [NBP3-12361] - A. PC-UBR1, B. Rat midbrain extract. Antibody diluted 1:500 in DiluObuffer. Apparent MW IS 210 KDa.
Immunohistochemistry-Paraffin: UBR1 Antibody [NBP3-12361]

Immunohistochemistry-Paraffin: UBR1 Antibody [NBP3-12361]

Immunohistochemistry-Paraffin: UBR1 Antibody [NBP3-12361] - Rat Kidney. 1:100 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnification.
Western Blot: UBR1 Antibody [NBP3-12361]

Western Blot: UBR1 Antibody [NBP3-12361]

Western Blot: UBR1 Antibody [NBP3-12361] - Mouse Cerebellum. 1:500 antibody dilution in DiluObuffer. Apparent MW is 210-215 KDa.
Immunohistochemistry-Paraffin: UBR1 Antibody [NBP3-12361]

Immunohistochemistry-Paraffin: UBR1 Antibody [NBP3-12361]

Immunohistochemistry-Paraffin: UBR1 Antibody [NBP3-12361] - Mouse Skeletal Muscle. 1:100 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnification.

Applications for UBR1 Antibody

Application
Recommended Usage

ELISA

1:4000

Immunohistochemistry

1:50-1:150

Immunohistochemistry-Paraffin

1:50-1:150

Immunoprecipitation

1:150

Western Blot

1:500

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.

Background: UBR1

The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome.

Alternate Names

E3 ubiquitin-protein ligase UBR1, E3a ligase, EC 6.3.2.-, JBS, MGC142065, MGC142067, N-recognin-1, ubiquitin ligase E3 alpha-I, ubiquitin protein ligase E3 component n-recognin 1, ubiquitin-protein ligase E3-alpha, Ubiquitin-protein ligase E3-alpha-1, Ubiquitin-protein ligase E3-alpha-I

Gene Symbol

UBR1

Additional UBR1 Products

Product Documents for UBR1 Antibody

Certificate of Analysis

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Product Specific Notices for UBR1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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