VCAM-1/CD106 Antibody (1027406) [Allophycocyanin]

Name: VCAM-1/CD106 Antibody (1027406) [Allophycocyanin]
Brand: Novus Biologicals
SKU: FAB11671A
Price: 529 USD
Availability: InStock

Novus Biologicals | Catalog # FAB11671A

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Monoclonal Mouse IgG₁ Clone # 1027406

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Product Specifications

Immunogen

Chinese Hamster Ovary cell line, CHO-derived human VCAM-1/CD106
Phe25-Glu698
Accession # P19320

Specificity

Detects recombinant human VCAM-1 in Direct ELISA.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for VCAM-1/CD106 Antibody (1027406) [Allophycocyanin]

Application

Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: VCAM-1/CD106

CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 ( alpha4/ beta1 integrin) and LPAM-1 ( alpha4/ beta7 integrin). The 429 antibody has been reported to partially block VCAM-1-mediated binding.

Long Name

Vascular Cell Adhesion Molecule 1

Alternate Names

CD106, VCAM1

Additional VCAM-1/CD106 Products

Product Documents for VCAM-1/CD106 Antibody (1027406) [Allophycocyanin]

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Certificate of Analysis

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Product Specific Notices for VCAM-1/CD106 Antibody (1027406) [Allophycocyanin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.