Catalog Number: 0654
Chemical Name: α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzeneacetonitrile hydrochloride
Biological Activity
L-type calcium channel blocker. Vasodilator, adrenergic antagonist.
Technical Data
  • M.Wt:
    491.07
  • Formula:
    C27H38N2O4.HCl
  • Solubility:
    Soluble to 50 mM in water
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    152-11-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Block of P-type Ca2+ channels in freshly dissociated rat cerebellar Purkinje neurons by diltiazem and verapamil.
    Ishibashi et al.
    Brain Res., 1995;695:88
  2. Interaction of RO-40-5967 and verapamil with the stably expressed α1-subunit of the cardiac L-type calcium channel.
    Lacinova et al.
    J.Pharmacol.Exp.Ther., 1995;274:54
  3. Effects of verapamil on intimal thickening and vascular reactivity in the collared carotid artery of the rabbit.
    Ustunes et al.
    Br.J.Pharmacol., 1996;118:1681
  4. Chemical modulators of autophagy as biological probes and potential therapeutics.
    Fleming et al.
    Nat.Chem.Biol., 2011;7:9

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