Verapamil hydrochloride

  ( 8 citations )    
Product Datasheet
Catalog Number:0654
Chemical Name:α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzeneacetonitrile hydrochloride
Product Details
Citations (8)
Reviews
Biological Activity
L-type calcium channel blocker. Vasodilator, adrenergic antagonist.
Technical Data
  • M.Wt:
    491.07
  • Formula:
    C27H38N2O4.HCl
  • Solubility:
    Soluble to 50 mM in water
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    152-11-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Verapamil hydrochloride include:

8 Citations: Showing 1 - 8
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  1. Ion Fluxes through KCa2 (SK) and Cav1 (L-type) Channels Contribute to Chronoselectivity of Adenosine A1 Receptor-Mediated Actions in Spontaneously Beating Rat Atria.
    Authors: Bragança Et al.
    Front Pharmacol  2016;7:45
  2. Binding of αherpesvirus Glycoprotein H to Surface α4β1-Integrins Activates Calcium-Signaling Pathways and Induces Phosphatidylserine Exposure on the Plasma Membrane.
    Authors: Azab Et al.
    FEMS Immunol Med Microbiol  2015;6
  3. Dissecting out the complex Ca2+-mediated phenylephrine-induced contractions of mouse aortic segments.
    Authors: Fransen Et al.
    Cereb Cortex  2015;10:e0121634
  4. Optimisation of embryonic and larval ECG measurement in zebrafish for quantifying the effect of QT prolonging drugs.
    Authors: Dhillon Et al.
    PLoS One  2013;8:e60552
  5. Areca nut-induced buccal mucosa fibroblast contraction and its signaling: a potential role in oral submucous fibrosis--a precancer condition.
    Authors: Chang Et al.
    PLoS One  2013;34:1096
  6. Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels.
    Authors: Xia Et al.
    Toxicol Appl Pharmacol  2011;252:250
  7. Calcium homeostasis and cone signaling are regulated by interactions between calcium stores and plasma membrane ion channels.
    Authors: Szikra Et al.
    PLoS One  2009;4:e6723
  8. Efficient intracellular multiplication of Legionella pneumophila in human monocytes requires functional host cell L-type calcium channels.
    Authors: Wieland Et al.
    Carcinogenesis  2006;47:296

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