Chemical Name: 3-Fluoro-5-(2-methyl-5-benzothiazolyl)-benzonitrile
Biological ActivityPotent negative allosteric modulator of mGlu5 (IC50 = 61 nM). Displays no activity at mGlu1-4 and mGlu7-8.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
(3-cyano-5-fluorophenyl)biaryl negative allosteric modulators of mGlu5: discovery of a new tool compound with activity in the OSS mouse model of addiction.
Lindsley et al.
ACS Chem.Neurosci., 2011;2:471
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VersaClone cDNA Plasmids
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