VX 702

  ( 2 citations )    
Product Datasheet
Catalog Number:3916
Chemical Name:6-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide
Product Details
Citations (2)
Reviews
Biological Activity
Orally active, ATP-competitive inhibitor of p38α MAPK; also inhibits p38β (KD values are 3.7 and 17 nM respectively).
Technical Data
  • M.Wt:
    404.32
  • Formula:
    C19H12F4N4O2
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    479543-46-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for VX 702 include:

2 Citations: Showing 1 - 2
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  1. Fractalkine shedding is mediated by p38 and the ADAM10 protease under pro-inflammatory conditions inhuman astrocytes.
    Authors: O'Sullivan Et al.
    Journal of Neuroinflammation  2016;13:189
  2. RNAi screen identifies MAPK14 as a druggable suppressor of human hematopoietic stem cell expansion.
    Authors: Baudet Et al.
    Blood  2012;119:6255

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