WWL 113

   
Product Datasheet
Catalog Number:5259
Chemical Name:4'-[[[Methyl[[3-(4-pyridinyl)phenyl]methyl]amino]carbonyl]oxy]-[1,1'-biphenyl]-4-carboxylic acid ethyl ester
Product Details
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Biological Activity
Carboxylesterase Ces3 and Ces1f inhibitor (IC50 values are ~100 nM). Also inhibits ABHD6. Exhibits minimal activity against a panel of other serine hydrolases. Promotes lipid storage in adipocytes. Reduces weight gain in diet-induced obese mice and enhances glucose tolerance in diabetic mice. Orally active.
Technical Data
  • M.Wt:
    466.53
  • Formula:
    C29H26N2O4
  • Solubility:
    Soluble to 50 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at -20°C
  • CAS No:
    947669-86-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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