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WY 45233 succinate

4194 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4194/10
4194/50
WY 45233 succinate | CAS No. 448904-47-0 | 5-HT Transporter Inhibitors
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Description: 5-HT and NA reuptake inhibitor (SNRI)
Alternative Names: Desvenlafaxine

Chemical Name: 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol succinate

Purity: ≥99%

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Biological Activity

Serotonin and noradrenalin reuptake inhibitor (SNRI); selective for human serotonin (SERT) and noradrenalin (NET) transporters against 96 other targets (Ki values are 40.2 and 558.4 nM for SERT and NET respectively). Inhibits [3H]5-HT and [3H]NE uptake (IC50 values are 47.3 and 531.3 nM). Salt form of the major active metabolite of venlafaxine (Cat. No. 2917).

Technical Data

M.Wt:
381.46
Formula:
C16H25NO2.C4H6O4
Solubility:
Soluble to 50 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
448904-47-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Product Datasheets

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VersaClone cDNA Plasmids

Human SLC6A2/NET (NP_001034) VersaClone cDNA

RDC1112

Human SLC6A2/NET (NP_001165975) VersaClone cDNA

RDC1141

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