Z-WEHD-FMK
Chemical Name: Benzyloxycarbonyl-Trp-Glu(OMe)-His-Asp(OMe)-fluoromethylketone
Biological Activity
Caspase-5 inhibitor. Inhibits ECyd-induced rRNA fragmentation in mouse mammary tumor and human fibrosarcoma cells.Technical Data
(Modifications: Trp-1 = Z-Trp, Glu-2 = Glu(OMe), Asp-4 = (OMe)-fluoromethylketone)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Anticancer mechanisms of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106).
Naito et al.
Nucl.Acids Res.Suppl., 2002;2:241
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