Evolution of Model Systems for Toxicology, Drug Screening, and Disease Modeling

This eBook provides a primer on the history, current state, and future use of cell-based 2-D and 3-D model systems for toxicology, drug screening, and disease modeling. Included are chapters on primary cells, cell lines, stem cells, 3-D cell culture models, and more complex tissue and organ modeling systems.

Key Topics

  • History of primary and cell lines for toxicology
  • Pluripotent stem cell models
  • 2-D vs. 3-D cell culture
  • Organoid benefits and challenges
  • MimEX 3-D Tissue Model Systems*
  • Future models and challenges

Interactive content and useful infographics:

  • ADME/Tox specifications
  • Commonly-used cell lines, categorized by organ
  • 2-D vs. 3-D model systems
  • Organoid reagent guide
  • MimEX 3-D Tissue Model Systems advantages
 
 

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