Evolution of Model Systems for Toxicology, Drug Screening, and Disease Modeling

This eBook provides a primer on the history, current state, and future use of cell based 2 D and 3 D model systems for toxicology, drug screening, and disease modeling. Included are chapters on primary cells, cell lines, stem cells, 3 D cell culture models, and more complex tissue and organ modeling systems.

Key Topics

• Primary and cell lines for toxicology
• Pluripotent stem cell models
• 2-D vs 3-D cell culture
• Organoid benefits and challenges
• Future models and challenges
• Toxicology assays

Infographics and Interactive Features for Cell Culture Models

• ADME/Tox specifications
• Commonly-used cell lines, categorized by organ
• 2-D vs 3-D model systems
• Organoid reagent guide

Related Information

Organoid and 3-D Cell Culture Resources and Reagents

Induced Pluripotent Stem Cell (iPSC) Reagents

Cultrex Basement Membrane Extracts and Extracellular Matrices

Serum-Free and Animal-Free Cell Culture