7 results for "5-HT1A Small Molecules and Peptides" in Products
5-HT1A Small Molecules and Peptides
5-HT1A is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin(1A) receptors, including 5-HT1A, belong to the family of G protein-coupled receptors and are implicated in the generation and modulation of various cognitive, behavioral and developmental functions. A relationship between 5-HT1A receptors and serotonin transporter (5-HTT) is also suggested by the pathophysiology of depression and the mechanism of action of antidepressants.
Endogenous 5-HT receptor agonist
| Alternate Names: | 5-Hydroxytryptamine,5-HT |
| Chemical Name: | 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride |
| Purity: | ≥98% |
5-HT1A, 5-HT1B and 5-HT1D agonist
| Alternate Names: | GR 43175 |
| Chemical Name: | 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate |
| Purity: | ≥99% |
5-HT1A and 5-HT1B agonist
| Chemical Name: | 5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate |
| Purity: | ≥99% |
Selective 5-HT1A agonist
| Alternate Names: | TVX Q 7821 |
| Chemical Name: | 2-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3(2H)-one-1,1-dioxide |
| Purity: | ≥99% |
Selective 5-HT1A partial agonist
| Alternate Names: | SM-3997 |
| Chemical Name: | (3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione hydrochloride |
| Purity: | ≥98% |
High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist
| Chemical Name: | 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone |
| Purity: | ≥99% |
Potent 5-HT1A partial agonist and SSRI; antidepressant
| Alternate Names: | EMD 68843,SB 659746A |
| Chemical Name: | 5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxamide hydrochloride |
| Purity: | ≥98% |