Abl Kinase Inhibitors: Products

c-Abl (Abelson murine leukemia viral homolog 1) is a cytosolic member of the ABL subfamily, protein tyrosine kinase family of enzymes. It is ubiquitously expressed, and participates in multiple processes such as cell migration, actin reorganization, DNA damage response and apoptosis.

"Abl Kinase Inhibitors" has 11 results in Products.
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Imatinib mesylate

Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit

Bosutinib

Dual Src-Abl inhibitor; antiproliferative

1-Naphthyl PP1

Src family kinase inhibitor; also inhibits c-Abl

Adaphostin

p210bcr/abl kinase inhibitor

AP 24534

Potent multi-kinase and pan-Bcr-Abl inhibitor

GNF 2

Selective allosteric inhibitor of Bcr-Abl tyrosine kinase activity

PPY A

Potent inhibitor of Abl T315l mutant and wild-type Abl kinases

GNF 5

Selective allosteric inhibitor of Bcr-Abl; analog of GNF 2 (Cat. No. 4399)

PKI 166 hydrochloride

Potent EGFR-kinase inhibitor

PD 180970

p210Bcr/Abl kinase inhibitor; also inhibits c-Src and KIT

AV 412

Potent inhibitor of EGFR, ErbB2 and Abl receptor tyrosine kinases
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