Having trouble trying to find the right product? Chat with our scientists below - we're here to help!

10 results for "BRD4 Small Molecules and Peptides" in Products

Sort by:

BRD4 Small Molecules and Peptides

BRD4 is encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq]

(+)-JQ1

Catalog #: 4499

(2)

Citations (44)

Product Documents

Potent and selective BET bromodomain inhibitor; cell permeable

Chemical Name:	(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester
Purity:	≥98%

I-BET 151 dihydrochloride

Catalog #: 4650

(2)

Citations (9)

Product Documents

BET bromodomain inhibitor; also promotes differentiation of hiPSCs into megakaryocytes

Chemical Name:	7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydroxy-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one dihydrochloride
Purity:	≥98%

XMD 8-92

Catalog #: 4132

Citations (13)

Product Documents

ERK5/BMK1 inhibitor; also BRD4 inhibitor

Chemical Name:	2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
Purity:	≥98%

PFI 1

Catalog #: 4445

Citations (6)

Product Documents

BET bromodomain inhibitor

Chemical Name:	2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
Purity:	≥98%

Bromosporine

Catalog #: 4758

Citations (2)

Product Documents

Broad spectrum bromodomain inhibitor

Chemical Name:	N-[(6-3-Methanesulfonamido-4-methylphenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate
Purity:	≥98%

CPI 203

Catalog #: 5331

(1)

Citations (3)

Product Documents

BET bromodomain inhibitor; arrests cell cycle at G1 phase

Alternate Names:	TEN 010
Chemical Name:	(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide
Purity:	≥98%

OTX 015

Catalog #: 6181

Citations (6)

Product Documents

BET bromodomain inhibitor; orally bioavailable

Alternate Names:	Birabresib
Chemical Name:	(6S)-4-(4-Chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide
Purity:	≥98%

I-BET 762

Catalog #: 6521

Citations (1)

Product Documents

Potent and high affinity BET bromodomain inhibitor; anti-inflammatory; orally bioavailable.

Alternate Names:	GSK525762A,Molibresib
Chemical Name:	(4S)-6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide
Purity:	≥98%