279 results for "BTK" in Products
BTK Products
Bruton tyrosine kinase (Btk) is a 75 kDa cytoplasmic protein tyrosine kinase that is widely expressed in hematopoietic cells. Btk is required for B cell receptor signaling and B cell development. Defects in Btk result in X-linked agammaglobulinemia which is characterized by a severely decreased level of circulating antibodies. Like other Tec family kinases, Btk contains a Pleckstrin homology domain, a Tec homology domain, an SH3 domain, an SH2 domain, and a protein kinase domain. Association of ...
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Flow, ICC/IF |
![Western Blot: BTK [p Tyr223] AntibodyBSA Free [NBP1-78295]](https://resources.rndsystems.com/images/products/BTK-[p-Tyr223]-Antibody-Western-Blot-NBP1-78295-img0004.jpg "Western Blot: BTK [p Tyr223] AntibodyBSA Free [NBP1-78295]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI3A2 |
| Applications: | IHC, WB, Flow, ICC/IF |
![Western Blot: BTK Antibody (OTI3A2) [NBP2-02472]](https://resources.rndsystems.com/images/products/BTK-Antibody-3A2-Western-Blot-NBP2-02472-img0002.jpg "Western Blot: BTK Antibody (OTI3A2) [NBP2-02472]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI3A2 |
| Applications: | IHC, WB, Flow, ICC/IF, CyTOF-ready |
![Western Blot: BTK Antibody (OTI3A2)Azide and BSA Free [NBP2-70291]](https://resources.rndsystems.com/images/products/BTK-Antibody-OTI3A2-Azide-and-BSA-Free-Western-Blot-NBP2-70291-img0001.jpg "Western Blot: BTK Antibody (OTI3A2)Azide and BSA Free [NBP2-70291]")
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #7F12H4 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: BTK Antibody (7F12H4)BSA Free [NB110-87047]](https://resources.rndsystems.com/images/products/BTK-Antibody-7F12H4-Western-Blot-NB110-87047-img0009.jpg "Western Blot: BTK Antibody (7F12H4)BSA Free [NB110-87047]")
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry-Paraffin: BTK Antibody [NBP1-89207]](https://resources.rndsystems.com/images/products/BTK-Antibody-Immunohistochemistry-Paraffin-NBP1-89207-img0011.jpg "Immunohistochemistry-Paraffin: BTK Antibody [NBP1-89207]")
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #7F12H4 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: BTK Antibody (7F12H4)Azide and BSA Free [NBP2-80605]](https://resources.rndsystems.com/images/products/BTK-Antibody-7F12H4-Azide-and-BSA-Free-Western-Blot-NBP2-80605-img0002.jpg "Western Blot: BTK Antibody (7F12H4)Azide and BSA Free [NBP2-80605]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #566928 |
| Applications: | WB, ICC/IF, Simple Western |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #797837 |
| Applications: | WB, Simple Western |
Highly potent pan-Src/Bcr-Abl inhibitor
| Alternate Names: | BMS-354825 |
| Chemical Name: | N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: BTK Antibody [NBP1-89206]](https://resources.rndsystems.com/images/products/BTK-Antibody-Western-Blot-NBP1-89206-img0010.jpg "Western Blot: BTK Antibody [NBP1-89206]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: BTK AntibodyBSA Free [NBP1-76596]](https://resources.rndsystems.com/images/products/BTK-Antibody-Western-Blot-NBP1-76596-img0003.jpg "Western Blot: BTK AntibodyBSA Free [NBP1-76596]")
Potent, selective BTK inhibitor
| Chemical Name: | 2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #720101 |
| Applications: | WB, ICC/IF |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #2J9O8 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: BTK Antibody (2J9O8) [NBP3-15612]](https://resources.rndsystems.com/images/products/BTK-Antibody-2J9O8-Western-Blot-NBP3-15612-img0004.jpg "Western Blot: BTK Antibody (2J9O8) [NBP3-15612]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: BTK [p Tyr223] Antibody [NBP3-12916]](https://resources.rndsystems.com/images/products/BTK-[p-Tyr223]-Antibody-Western-Blot-NBP3-12916-img0001.jpg "Western Blot: BTK [p Tyr223] Antibody [NBP3-12916]")
| Reactivity: | Human |
| Source: | Sf 21 (baculovirus) |
| Accession #: | Q06187.3 |
| Applications: | Enzyme Activity |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #3005A |
| Applications: | WB |
Potent and selective BTK inhibitor
| Chemical Name: | 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one |
| Purity: | ≥98% |
Potent and selective BTK Degrader (PROTAC®)
| Chemical Name: | 4-(1,1-Dimethylethyl)-N-[3-[6-[[4-[[4-[6-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]acetyl]amino]hexyl]-1-piperazinyl]carbonyl]phenyl]amino]-4,5-dihydro-4-methyl-5-oxo-2-pyrazinyl]-2-methylphenyl]benzamide |
| Purity: | ≥98% |
Potent ITK inhibitor; also inhibits BTK
| Chemical Name: | (R)-3-(1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(3-methyl-4-(1-methylethyl))benzamide |
| Purity: | ≥95% |
Potent BTK inhibitor
| Chemical Name: | 1-Cyclopentyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% |
Potent c-SRC kinase inhibitor; also inhibits DDR2, BTK and Syk
| Chemical Name: | 3-[[2-[3-(4-Morpholinylmethyl)phenyl]thieno[3,2-b]pyridin-7-yl]amino]phenol dihydrochloride |
| Purity: | ≥98% |
Potent, reversible BTK inhibitor
| Chemical Name: | N-[3-[4,5-Dihydro-4-methyl-6-[[4-(4-morpholinylcarbonyl)phenyl]amino]-5-oxo-2-pyrazinyl]-2-methylphenyl]-4-(1,1-dimethylethyl)benzamide |
| Purity: | ≥97% |
| Reactivity: | Human |
| Applications: | AC |
![BTK [p Tyr223] Antibody Blocking Peptide](https://resources.rndsystems.com/images/icons/RnD-Default-Product-Image_Proteins-Icon.svg "BTK [p Tyr223] Antibody Blocking Peptide"){kind=icon}
| Reactivity: | Human |
