7 results for "Compounds for NSC Proliferation and Renewal Small Molecules and Peptides" in Products

Compounds for NSC Proliferation and Renewal Small Molecules and Peptides

Pluripotent Stem Cell Maintenance

Proliferation and self-renewal of stem cells occurs via the division of a cell into two identical daughter cells, resulting in the production of cells identical to the parent. Unlike other cell types, such as muscle or blood cells, stem cells are able to replicate many times. Under the right conditions stem cells can continue to proliferate in culture over many months without differentiation and specialization, yielding millions of cells; this is known as ...

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Selective inhibitor of p38 MAPK

Alternate Names: Adezmapimod
Chemical Name: 4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine
Purity: ≥98%
Selective inhibitor of p38 MAPK
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FGFR1 and -3 inhibitor

Chemical Name: N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea
Purity: ≥98%
FGFR1 and -3 inhibitor
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Potent pan-caspase inhibitor

Chemical Name: N-[2-(1,1-Dimethylethyl)phenyl]-2-oxoglycyl-N-[(1S)-1-(carboxymethyl)-2-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl]-L-alaninamide
Purity: ≥98%
Potent pan-caspase inhibitor
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Notch signaling pathway activator; enhances the self-renewal capability of NSCs; active in vivo

Chemical Name: 5-(3-Methoxyphenoxy)-N2-[4-(1-methylethyl)phenyl]-2,4-quinazolinediamine hydrochloride
Purity: ≥98%
Notch signaling pathway activator; enhances the self-renewal capability of NSCs; active in vivo
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DYRK1A/B inhibitor

Chemical Name: (1Z)-1-(3-Ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone
Purity: ≥98%
DYRK1A/B inhibitor
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Selective GPR55 agonist; also promotes NSC proliferation and differentiation

Alternate Names: CID 20440433
Chemical Name: 3-[[4-(2,3-Dimethylphenyl)-1-piperazinyl]carbonyl]-N,N-dimethyl-4-(1-pyrrolidinyl)benzenesulfonamide
Purity: ≥98%
Selective GPR55 agonist; also promotes NSC proliferation and differentiation
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Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture

Chemical Name: N-Propyl-3-(4-pyridinyl)imidazo[1,2-b]pyridazin-6-amine
Purity: ≥98%
Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture
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