7 results for "Dyrk1B Small Molecules and Peptides" in Products
Dyrk1B Small Molecules and Peptides
DYRK1B is a member of the DYRK family of protein kinases. DYRK1B contains a bipartite nuclear localization signal andis found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions.Three isoforms of DYRK1B have been identified differing in the presence of two alternatively spliced exons within thecatalytic domain. (provided by RefSeq)
Potent and selective DYRK1A/B inhibitor
| Alternate Names: | R05454948 |
| Chemical Name: | N-[2-Chloro-5-[[[(3-chlorophenyl)methyl]amino]carbonyl]phenyl]-7,8-dihydro-2-methoxy-7-oxopyrido[2,3-d]pyrimidine-6-carboxamide |
| Purity: | ≥98% |
Potent DYRK1B inhibitor
| Chemical Name: | N-[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-pyrimidinamine |
| Purity: | ≥98% |
Potent and selective Dyrk1B kinase inhibitor
| Chemical Name: | 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine |
| Purity: | ≥98% |
Inhibitor of Clk and DYRK kinases
| Chemical Name: | 5-(1,3-Benzodioxol-5-yl)-N-[(3,5-dichlorophenyl)methyl]-4-pyrimidinamine hydrochloride |
| Purity: | ≥98% |
Potent and selective ATP-competitive CDK9 inhibitor
| Chemical Name: | 4-[[[5'-Chloro-2'-[[trans-4-[[(1R)-2-methoxy-1-methylethyl]amino]cyclohexyl]amino][2,4'-bipyridin]-6-yl]amino]methyl]tetrahydro-2H-pyran-4-carbonitrile |
| Purity: | ≥97% |
Potent and selective DYRK inhibitor; orally bioavailable.
| Chemical Name: | (5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-4(5H)-thiazolone |
| Purity: | ≥95% |
Potent and selective pan-CLK inhibitor; also inhibits DYRK1A/B
| Chemical Name: | 4-[1,1-Dimethyl-2-(4-methyl-1-piperazinyl)-2-oxoethyl]-N-[6-(4-pyridinyl)imidazo[1,2-a]pyridin-2-yl]benzamide |
| Purity: | ≥98% |
